Effect of Apis dorsata and Tetragonula biroi honey in the levels of glutathione and attenuation of cyclophosphamide-induced genotoxicity in mice (Mus musculus linn.)

Please use this identifier to cite or link to this item: http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/781

Full metadata record

DC Field	Value	Language
dc.contributor.author	Antonio, Lorenzo Daniel L.	-
dc.contributor.author	Tan, Rochelle Anne R.	-
dc.date.accessioned	2021-08-12T01:25:13Z	-
dc.date.available	2021-08-12T01:25:13Z	-
dc.date.issued	2016-05	-
dc.identifier.uri	http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/781	-
dc.description.abstract	The effect of Apis dorsata and Tetragonula biroi honey against cyclophosphamideinduced genotoxicity in Mus musculus Linn. was determined through studying the effects of CP and honey on micronucleus formation, chromosomal aberrations, mitotic index, and hepatic reduced glutathione (GSH) levels. Results show that CP significantly decreased GSH levels in liver tissues by 34%. CP also induced significant increases in chromosomal aberrations and micronucleus formation by 600% and 163%, respectively. Treatment of honey ameliorated GSH levels, micronuclei counts, and chromosomal aberrations comparable to negative controls. Thus, administration of A. dorsata and T. biroi honey reduce the risk of CP-induced cytotoxicity and genotoxicity in M. musculus	en_US
dc.language.iso	en	en_US
dc.subject	Apis dorsata	en_US
dc.subject	Tetragonula biroi honey	en_US
dc.title	Effect of Apis dorsata and Tetragonula biroi honey in the levels of glutathione and attenuation of cyclophosphamide-induced genotoxicity in mice (Mus musculus linn.)	en_US
dc.type	Thesis	en_US
Appears in Collections:	BS Biology Theses

Files in This Item:

File	Description	Size	Format
CD-C135.pdf Until 9999-01-01		12.45 MB	Adobe PDF	View/Open Request a copy

DSpace JSPUI