Molecular Dating and Anthropogenetics of MicroRNAs in Segmentally-duplicated Regions: an Insight on the Origin of Human Intelligence

Pardo, Lyndon Aries A.; Sobremisana, James A.

dc.contributor.author	Pardo, Lyndon Aries A.
dc.contributor.author	Sobremisana, James A.
dc.date.accessioned	2022-09-22T02:51:28Z
dc.date.available	2022-09-22T02:51:28Z
dc.date.issued	2010-03
dc.identifier.uri	http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/1570
dc.description.abstract	We have reconstructed the hominid evolution line by dating the brain miRNA divergence in accordance with the developments of hominid intelligence after splitting from the chimpanzee line. Homology between human and chimpanzee brain miRNAs was determined and dated by obtaining their non-synonymous substitutions (Ks) over the past millions of years. A phylogenetic tree of miRNAs was constructed to verify if dates of segmental duplication is in accord in the sequence of emergence of miRNAs. Seven (7) miRNAs that have arisen from segment duplication events suggest human-specific genes that might have caused the intelligence of humans.	en_US
dc.title	Molecular Dating and Anthropogenetics of MicroRNAs in Segmentally-duplicated Regions: an Insight on the Origin of Human Intelligence	en_US
dc.type	Thesis	en_US