DSpace JSPUI
DSpace preserves and enables easy and open access to all types of digital content including text, images, moving images, mpegs and data sets
Learn More
Please use this identifier to cite or link to this item:
http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/3582| Title: | Effects of Cyclooxygenase Inhibitors on the Radiation Response of Intestinal Crypt Cells in Male Mice |
| Authors: | Dones, Rosa Angela SA. Serna, Paulene-Ver A. |
| Keywords: | cyclooxygenase COX inhibitors radiation intestinal crypt cells regenerating cells radioprotective agent |
| Issue Date: | Mar-2002 |
| Abstract: | The effects of varying doses of different types of Cyclooxygenase (COX) inhibitors on irradiated and nonirradiated murine intestinal crypt cells were investigated. Cell counts, supported by data from TUNEL assay and immunohistochemical analyses, revealed that apoptosis was greatest in irradiated tissues treated with NSAIDS. Irradiated cells treated with COX-2 inhibitors showed least occurrence of apoptosis with increased occurrence of regenerating cells. Results suggest a potential role of COX- 2 selective inhibitors as a radioprotective agent for normal cells in radiation therapy. |
| URI: | http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/3582 |
| Appears in Collections: | BS Biology Theses |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2002_Dones RASA_Serna PVA_Effects of Cyclooxygenase Inhibitors on the Radiation Response of Intestinal Crypt Cells in Male Mice.pdf Until 9999-01-01 | 12.62 MB | Adobe PDF | View/Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.