Potential Antitumor and Immunological Properties of Acylglucosylsterol from Moringa oleifera (Malunggay) Seeds

Apostol, Angela S.; Ocampo, Mary Ann M.

dc.contributor.author	Apostol, Angela S.
dc.contributor.author	Ocampo, Mary Ann M.
dc.date.accessioned	2025-03-19T00:16:54Z
dc.date.available	2025-03-19T00:16:54Z
dc.date.issued	2003-04
dc.identifier.uri	http://dspace.cas.upm.edu.ph:8080/xmlui/handle/123456789/2967
dc.description.abstract	One of the bioactive compounds that has been isolated from various parts of Moringa oleifera (malunggay) is 3-O-[6’-0O-oleoyl-B-D-glucosyl]-B-sitosterol, generally known as acylglucosylsterol. Isolation of this compound involves solvent fractionation, liquid column chromatography and thin layer chromatography. The isolated compound was tested for its cytotoxic effect on leukemic cells. A cytotoxicity assay, based on blue trypan dye exclusion method, revealed an LC50 of 38 mg/ml. en leukemic cells. Administration of acylglucosylsterol was also found to cause changes in the differential leukocyte counts of ICR strain albino mice injected with 22% bovine serum albumin as immunogen.	en_US
dc.subject	Antitumor	en_US
dc.subject	Immunological	en_US
dc.subject	Acylglucosylsterol	en_US
dc.subject	Moringa Oleifera	en_US
dc.subject	Malunggay	en_US
dc.subject	Bioactive Compounds	en_US
dc.subject	Leukemic Cells	en_US
dc.subject	Cytotoxicity Assay	en_US
dc.title	Potential Antitumor and Immunological Properties of Acylglucosylsterol from Moringa oleifera (Malunggay) Seeds	en_US
dc.type	Thesis	en_US