The Radioprotective Potential of Spirulina Tablets on Irradiated Mouse Bone Marrow Cells

Abstract

In the testing of the radioprotective potential of Spirulina tablets, the micronucleus test was utilized. A total of 15 mice were used. The average weight of the mice were obtained and the dosage administered was calculated. Distilled water was used for negative control and Beta carotene was used for positive control. The negative control mice were not exposed to radiation while Spirulina and Beta carotene treated mice were irradiated. Results showed that there was a lower micronucleus frequency in Spirulina tablets and Beta carotene capsules treated mice than distilled water treated mice though exposed to radiation. Statistical analysis showed that there is no sufficient evidence that Spirulina treated mice is not equal to the distilled water and Beta carotene treated mice since the h value = 3.84 is less than the critical region which is 5.991. From the data obtained, it can be deduced that Spirulina tablets exhibited radioprotective effect on irradiated mouse bone marrow cells.